Witten J, Ruschak A, Poterba T, Jaramillo A, Miranker AD, Jaswal SS. (2015) Mapping protein conformational lanscapes under strongly native conditions with hydrogen exchange mass spectrometry. J Phys Chem B. 119(31):10016-24. PDF

Nath A, Schlamadinger DE, Rhoades E, Miranker AD. (2015) Structure-based small molecule modulation of a pre-amyloid state: Pharmacological enchancement of IAPP membrane-binding and toxicity. Biochemistry. 54(22):3555-64. PDF

Kumar S, Schlamadinger DE, Brown MA, Dunn JM, Mercado B, Hebda JA, Saraogi I, Rhoades E, Hamilton AD, Miranker AD. (2015) Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based alpha-helical mimetics. Chem Biol. 22(3):368-78. PDF

Rubio MA, Schlamadinger DE, White EM, Miranker AD. (2015) Peptide amyloid surface display. Biochemistry. 54(4):987-93. PDF

Schlamadinger DE, Miranker AD. (2014) Fiber-dependent and -independent toxicity of islet amyloid polypeptide.  Biophys J. 107(11):2559-66. PDF

Hebda JA, Magzoub M, Miranker AD. (2014) Small molecule screening in context: lipid-catalyzed amyloid formation. Protein Sci. (10):1341-8. PDF

Kumar S, Brown MA, Nath A, Miranker AD. (2014) Folded Small Molecule Manipulation of Islet Amyoid Polypeptide. Chem Biol. 21(6):775-81. PDF

Last NB, Schlamadinger DE, Miranker AD. (2013) A common landscape for membrane-active proteins.  Protein Sci. 7, 870-82.  PDF

Kumar S, Miranker AD. (2013) A foldamer approach to targeting membrane bound helical states of islet amyloid polypeptide. Chem. Commun. 49, 4749-4751. PDF

Last NB, Miranker AD. (2013) Common mechanism unites membrane poration by amyloid and antimicrobial peptides. Proc Natl Acad Sci U S A. 110(16):6382-7. PDF

Magzoub M, Miranker AD. (2012) Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide. FASEB J. 26(3):1228-38. PDF

Nath A, Miranker AD, Rhoades E. (2011) A membrane-bound antiparallel dimer of rat islet amyloid polypeptide. Angew Chem Int Ed Engl. 50(46):10859-62. PDF

Last NB, Rhoades E, Miranker AD. (2011) Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity. Proc Natl Acad Sci U S A108(23):9460-5. PDF

Magzoub M, Miranker AD. (2011) Protein aggregation: p53 succumbs to peer pressure. Nat Chem Biol. 7(5):248-9. PDF

Wolfe LS, Calabrese MF, Nath A, Blaho DV, Miranker AD, Xiong Y. (2010) Protein-induced photophysical changes to the amyloid indicator dye thioflavin T. Proc Natl Acad Sci U S A. 107(39):16863-8. PDF

Nath A, Trexler AJ, Koo P, Miranker AD, Atkins WM, Rhoades E. (2010) Single-molecule fluorescence spectroscopy using phospholipid bilayer nanodiscs. Methods Enzymol. 472:89-117. PDF

Saraogi I, Hebda JA, Becerril J, Estroff LA, Miranker AD, Hamilton AD. (2009) Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation. Angew Chem Int Ed Engl. EPub

Hebda J. A., Saraogi I, Magzoub M, Hamilton A. D, Miranker AD. (2009) A peptidomimetic approach to targeting pre-amyloid states in type II diabetes. Chem Biol. 16(9):943-50. PDF

Williamson J. A., Loria J. P., Miranker A. D. (2009) Helix stabilization precedes acquaeous and bilayer-catalyzed fiber formation in islet amyloid polypeptide. J Mol. Biol. 393(2):383-96. PDF

Ruschak, A. M. and MIranker, A. D. (2009) The role of prefibrillar structures in the assembly of a polypeptide amyloid. J Mol. Biol. 393(1):214-26. PDF

Blaho, D. V. and Miranker, A. D. (2009) Deleniating the conformational elements responsible for Cu(II)-induced oligomerization of beta-2 Microglobulin. Biochemistry 48: 6610-6617. PDF

Hebda, J. A. and Miranker, A. D. (2009) The Interplay of Catalysis and Toxicity by Amyloid Intermediates on Lipid Bilayers: Insights from Type II Diabetes.Annu Rev Biophys 38: 125-52. PDF

Calabrese, M. F. and Mirakner, A. D. (2009) Metal binding sheds light on mechanism of amyloid assembly. Prion 3 (1): 1-4. PDF

Knight, J. D., Williamson, J. A. and Miranker, A. D. (2008) Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin.Protein Sci. 17 (10): 1850-6. PDF

Calabrese, M. F., et. al. (2008) A regulatable switch mediates self-association in an immunoglobulin fold. NSMB 15: 965-71. PDF

Koo, B. W. Hebda, J. A. and Miranker, A.D. (2008) Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide. Protein Eng Des Sel. 21 (3): 147-54. PDF

Jaswal, S. S. and Miranker, A. D. (2007) Scope and utility of hydrogen exchange as a tool for mapping landscapes. Protein Sci. 16 (11): 2378-90.PDF

Ruschak, A.R. and Miranker, A.D. (2007) Fiber-dependent amyloid formation as catalysis of an existing reaction pathway. PNAS 104: 12341-6. PDF

Calabrese, M.F. and Miranker, A.D. (2007) Formation of a Stable Oligomer of beta-2 Microglobulin Requires only Transient Encounter with Cu(II). JMB 367: 1-7. PDF

Williamson, J.A., and Miranker, A.D. (2007) Direct detection of transient alpha-helical states in islet amyloid polypeptide. Protein Sci 16: 110-117. PDF

Knight, J. D., Hebda, J. A., Miranker, A. D. (2006) Conserved and cooperative assembly of membrane-bound states of islet amyloid polypeptide. Biochemistry, 45(31):9496-508. PDF

Eakin, C. M., Berman, A. J., Miranker, A. D. (2006) A native to amyloidogenic transition regulated by a backbone trigger. NSMB 13:202-208. PDF

Eakin, C. M. and Miranker, A.D. (2005) From chance to frequent encounters: Origins of beta 2-microglobulin fibrillogenesis. Biochim. Biophys Acta 1753:92-9. PDF

Miranker A. D. (2005) Quantitative Measurement of Fibrillogenesis by Mass Spectrometry. Methods Mol Biol 299:185-194. PDF

Miranker, A.D. (2005). Structural biology - Fibres hinge on swapped domains. Nature 437:197-198. PDF

Koo B.W., Miranker A.D. (2005). Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid. Protein Science 14:231-239. PDF

Knight, J.D. and Miranker, A.D. (2004). Phospholipid catalysis of diabetic amyloid assembly. J. Mol. Biol. 341:1175-1187. PDF

Miranker A.D. (2004). Unzipping the mysteries of amyloid fiber formation. Proc. Natl. Acad. Sci. (USA) 101:4335-4336. PDF

Eakin C. M., Attenello F.J. , Morgan C.J. and Miranker A.D. (2004). Oligomeric assembly of native-like precursors precedes amyloid formation by B-2 Microglobulin. Biochemistry 43:7808-7815. PDF

Larson, J.L. and Miranker, A.D. (2004). The mechanism of insulin action on islet amyloid polypeptide fiber formation. J. Mol. Biol. 335:221-31. PDF

Eakin, C., Knight, J., Morgan, C., Gelfand, M. and Miranker. A.D. (2002) Formation of a copper specific binding site in non-native states of Beta-2-Microglobulin. Biochemistry. 41:10646-10656 PDF

Padrick, S. and Miranker. A.D. (2002) Islet amyloid: phase partitioning and secondary nucleation are central to the mechanism of firillogenesis. Biochemistry. 41:4694-4703 PDF

Morgan, C., Gelfand, M., Atreya, C. and Miranker, A. D. (2001) Kidney dialysis-associated amyloidosis: a molecular role for copper in fibril formation J. Mol. Biol. 309:339-345 PDF

Padrick, S. Miranker, A. D. (2001) Islet amyloid polypeptide: Identification of long range contacts and local order on the fibrillogenesis pathway J. Mol. Biol. 308:783-794 PDF

Larson, J. L., Ko, E. Miranker, A. D. (2000) Direct measurement of islet amyloid polypeptide fibrillogenesis by mass spectrometry. Protein Science 9:427-431PDF

Miranker A. D. (2000). Protein complexes and analysis of their assembly by mass spectrometry Curr Opin Struct Biol 10:601-606 PDF

Miranker, A. D. (2000). Mass spectrometry of proteins of known mass Proc Natl Acad Sci (USA) 97:14025-70 PDF

Weber-ban, E. Reid, B.G. Miranker, A.D. Horwich, A. L. (1999). Global unfolding of a substrate protein by the Hsp100 chaperone ClpA. Nature 401:90-93 PDF

Canet, D., Sunde, M., Last, A. M., Miranker, A., Spencer, A., Robinson, C. V., Dobson, C. M. (1999). Mechanistic studies of the folding of human lysozyme and the origin of amyloidogenic behavior in its disease-related variants. Biochemistry 38:6419-6427. PDF

Morgan, C. J., Miranker, A. and Dobson, C. M. (1998). Characterization of collapsed states in the early stages of the refolding of hen lysozyme. Biochemistry 37:8473-8480. PDF